Free shipping above 49 Euro
100 Day Money Back Guarantee
Secure shopping with SSL

Buy more, save more - Up to 20% off

How to combine vitamin D and vitamin K properly

Mar 25, 2022




How to combine vitamin D and vitamin K properly

Why You Need Both Vitamin D3 and Vitamin K2

 Vitamin D3 helps your body absorb calcium from the diet. But without enough vitamin K2, that calcium may not be directed where it’s needed such as your bones and teeth and can instead end up in soft tissues like arteries, potentially leading to calcification and arteriosclerosis.

Vitamin K2 activates specific proteins such as osteocalcin and matrix Gla-protein (MGP) that:

  • Direct calcium into bones and teeth
  • Prevent calcium buildup in arteries and soft tissues

In short: Vitamin D3 increases calcium availability, while vitamin K2 ensures it’s used properly.

The Synergistic Relationship

Taking vitamin D increases the body’s production of vitamin K2-dependent proteins. But without enough K2, these proteins remain inactive, and calcium can go to the wrong places. Together, D3 and K2:

  • Strengthen bones
  • Support heart and vascular health
  • Reduce the risk of osteoporosis and arteriosclerosis

The right vitamin K2 dosage depends on your age, health status, and whether you're taking vitamin D3:

Vitamin K2 DosageWho It’s For
45 mcg/day- People on vitamin K antagonist anticoagulants
- Healthy individuals under 50 not taking D3 supplements
100 mcg/day- Healthy individuals
- Anyone taking up to 2,500 IU of vitamin D3/day
200 mcg/day- People with a family history or symptoms of cardiovascular disease or osteoporosis
- Anyone taking more than 2,500 IU of vitamin D3/day

Important: If you’re taking anticoagulants, consult your doctor before using vitamin K2 supplements.

Your body makes vitamin D3 through sun exposure, but most people don’t get enough year-round. Aim for a blood level of 50–80 ng/ml of 25(OH)D.

Vitamin D3 DosageWhen to Use It
2,500–5,000 IU/dayFor most people to maintain optimal levels
>5,000 IU/dayOnly with regular blood testing every 3 months

Best Practices for Combining Vitamin D3 and K2

  • Take both daily, preferably with meals for better absorption.
  • K2 dosage stays consistent regardless of your D3 intake. Always aim for 100 to 200 mcg per day for optimal benefit.
  • Adjust D3 based on your sun exposure and get your 25(OH)D levels tested to find the right dosage.

The Science Behind Vitamin K2

Vitamin K2 activates two vital proteins:

  • Osteocalcin – helps bind calcium to the bone matrix
  • Matrix Gla Protein (MGP) – prevents calcium from depositing in arteries

Without vitamin K2, calcium can accumulate in the wrong places—even when taking vitamin D3. This imbalance can contribute to:

  • Arterial calcification
  • Weakened bones
  • Higher cardiovascular risk

Conclusion

Vitamin D3 and vitamin K2 are a powerful team that work best when taken together. If you’re supplementing with vitamin D3, don’t overlook K2. The right balance supports your bones, heart, and overall health while avoiding the risks of misplaced calcium.


Recommended products

Related blogs

VE_Kategoriebilder_Vitamin-K2_600x600px.jpg

Buying Vitamin K2 - what you need to know!

VE_Kategoriebilder_Vitamin-D-Dosierung_600x600px.jpg

Vitamin D dosage - This much is really necessary

VE_Titel-und-Beitragsbilder_Vitamin-D_300x300px.jpg

Vitamin D: Vital for health

VE_Kategoriebilder_Vitamin-D-Wie-gefährlich-Mangel_600x600px.jpg

How to determine the Vitamin D3 level


Customers about us
Everything all right
Gosto particularmente dos produtos e das informações sobre os mesmos. Detesto a empresa transportadora que quase nunca entrega as encomendas nos prazos a que se comprometem, e, particularmente nesta ultima encomenda. que fui inicialmente informado que chegaria no dia 28 de Abril, posterior mente mandaram-me um mail a alterar a entrega para 29. Hoje, quando estou a preencher o vosso inquérito, é 2 de Maio, 9 horas da manhã, e ainda não recebi nada nem me mandaram nenhuma informação.
Perfect
I always find what I am looking for on Vitamin Express. The products are of the highest quality.
Super god service, og rigtig god produkter :-) I love it
Show all reviews
Your benefits
  • FREE SHIPPING
    for orders above 49 Euro
  • 100 DAY MONEY BACK GUARANTEE
    if unsatisfied
  • SAVE UP TO 20%
    with our volume discounts and 5% cart bonus
  • EASY PAYMENT
    Credit Card, PayPal, Pay over time, Google Pay, Apple Pay