According to studies, about half of all women of childbearing age suffer from the so-called premenstrual syndrome (PMS).  This generic term stands for menstrual pains and discomfort that can start as early as 1-2 weeks before menstruation and can last throughout the period. Mood swings, cramps and fatigue are just 3 of the unpleasant symptoms associated with PMS.
The well-tolerated nutritional supplement for periods PRE MENSTRUAL SYNERGY was specially developed to alleviate this discomfort. With a harmonious blend of valuable plant extracts, bioactive vitamins and essential minerals, the supplement for alleviating PMS provides a holistic 6-in-1 effect.
The question of what causes premenstrual syndrome has not yet been conclusively answered by science. Researchers suspect a connection between menstrual pains and discomfort and hormonal processes that occur in the female body before and during the period.
During this time, the balance of levels of sex hormones estrogen and progesterone can be disrupted. This in turn can hinder the release of the neurotransmitter dopamine as well as of serotonin, the "happiness hormone". This results in low moods, which can also manifest themselves physically in sensitive individuals.
PRE MENSTRUAL SYNERGY can support the female body in maintaining its natural balance during the menstrual cycle. With PMS, vitamins are essential to support normal functioning of the body's processes. In this nutritional supplement for periods, they are featured in their bioavailable form and are therefore more easily absorbed by the body. In addition, the supplement contains plant extracts that have been used in natural medicine to treat period pains and discomfort for centuries. The balanced formula is rounded off by valuable minerals.
Many PMS products are targeted at only one symptom. This is not very effective, as period complaints are often interconnected. Thus, abdominal pain can disturb sleep, and a restless night can make mood disorders worse.
PRE MENSTRUAL SYNERGY has a broadly based formula. Carefully combined ingredients can help the body to break the vicious monthly circle of period pain and discomfort.
In alternative medicine, saffron has been used for centuries to relieve female period complaints, primarily as a natural mood enhancer. Clinical studies confirm the balancing effect of the plant on the human mood.  [[D904]] In a study conducted by Tehran University of Medical Sciences on women between the ages of 18 and 45, 60% of the subjects reported a 50% improvement in their mood. 
PRE MENSTRUAL SYNERGY contains saffron as a high-quality Safr'InsideTM extract in Sargol quality. In research on the effect of Safr'InsideTM, 77% of subjects felt an increased sense of confidence, and 75% confirmed that their emotional balance had improved. 
As a nutritional supplement for periods, PRE MENSTRUAL SYNERGY combines saffron extract and lemon balm. They mutually reinforce their mood-lifting effects. Natural lemon balm supports cognitive function and contributes to a feeling of physical and mental relaxation. It can help the body maintain a balance between the "stress hormone" cortisol and the "happiness hormone" serotonin – a basic prerequisite for restful sleep.
In PMS products such as PRE MENSTRUAL SYNERGY, lemon balm is an optimal ingredient, as sleep disturbances commonly accompany the syndrome. Initial studies on the effect of lemon balm in PMS confirmed the positive effect of the plant extract on the female body. 
In naturopathy, vitex and lady's mantle are commonly used remedies for menstrual pain and discomfort. Lady's mantle is valued in alternative medicine for its contribution to general well-being before and during periods.  A study on vitex confirmed the plant's positive impact on women's moods during the menstrual cycle.  Together, the extracts can reduce fatigue, weariness, and discomfort – common symptoms of PMS.
Many of the typical PMS-related complaints are caused by disrupted hormone balance. As a nutritional supplement for periods, PRE MENSTRUAL SYNERGY contains vitamin B6 in its bioactive form of pyridoxal 5'-phosphate (PLP). As one of the most effective vitamins for PMS, it helps regulate hormone activity. It also supports the normal functioning of the nervous system and energy metabolism.
For some women, discomfort before and during periods can negatively affect performance at school, university or work. PRE MENSTRUAL SYNERGY contains vitamin B12 as a solution against a decrease in performance. It is available in the directly usable form methylcobalamin, so that the complex splitting process in the body is not necessary.
Hormonal fluctuations during the menstrual cycle can cause redness, blemishes and oily scalp. The combination of biotin, zinc and selenium can counteract this. Biotin, the "beauty vitamin", contributes to maintaining normal skin and hair. 
The mineral zinc complements this effect. In the body, zinc is involved in a number of important processes, including cell division. Zinc is important in PMS supplements, because affected women may have a zinc deficiency.  
Selenium rounds out the beauty mix in the PMS formula. The essential mineral contributes to the protection of cells against oxidative stress and thus helps support beautiful skin and hair.
For the aforementioned vitamin B12 to unfold its effect, it is dependent on folate. In this high-quality nutritional supplement for periods, the water-soluble vitamin is featured in the active form of 5-methylfolate (MTHF) or Quatrefolic. The body can use it immediately without expending effort to break it down with the help of enzymes. Folate contributes to normal cognitive function and cell division. It can help the body maintain its normal energy level even during menstruation.
The essential mineral magnesium serves as a cofactor for around 600 of the body's own enzymes, without which they could not carry out their functions. Among others, these processes affect the electrolyte balance, energy metabolism and the nervous system. Magnesium supports normal muscle function – including that of the uterine muscle. Women affected by PMS often suffer from lower abdominal pain before and during the period. Studies show that an adequate intake of magnesium can alleviate these muscle cramps. 
The nutritional supplement for periods is suitable for all women who suffer from menstrual pains and discomfort and want to experience more wellbeing during their menstrual cycle. The high-quality formula is particularly effective against sleep disturbances, depressed mood, mood swings and exhaustion. These are among the most common PMS symptoms.
Taking PRE MENSTRUAL SYNERGY is also recommended in case of cycle-related skin impurities, oily scalp and brittle nails. Unlike other one-dimensional PMS supplements, the formula contains both vitamin B12 and biotin. As a powerful duo, these two can contribute to beautiful skin, hair and nails.
PRE MENSTRUAL SYNERGY is based on a gluten-free and lactose-free formula with no known side effects. Adhere to the recommended daily dose of one capsule, taking it with sufficient liquids.
Give your body enough time to benefit from the valuable ingredients of the PMS supplement. The best effect is achieved when the product is taken continuously for at least 3 period cycles.
Nutritional supplements are not a substitute for a balanced diet and should always be taken as part of a healthy eating plan and lifestyle.
Servings per day
Supply for days
Price per kg/l
€647.73 / 1KG incl. VAT
1 capsule daily with a glass of water after a meal.
Magnesium Oxide, Coating Agent: Hydroxypropylmethyl Cellulose (capsule), Lemon Balm Leaf Extract with 2,5% Rosmarinic Acid (X%; Melissa officinalis L.), Lady's Mantle Aerial Part Extract (X%; Alchemilla vulgaris L.), Bulking Agent: Cellulose, Saffron Stigmas Extract with 12% Safromotivines (X%; Crocus sativus L.), Zinc Bisglycinate, Chasteberry Fruit Powder (X%; Vitex agnus-castus L.), L-Selenomethionine, Anti-Caking Agent: Cellulose, D-Biotin (Biotin), Pyridoxal 5'-Phosphate (Vitamin B6), Black Pepper Fruit Extract with 95% Piperine (X%; Piper nigrum), (6S)-5-Methyltetrahydrofolic Acid Glucosamine Salt (Folate), Methylcobalamin (Vitamin B12) / Suitable for Vegetarians and Vegans.
1 Capsule contains:
* % of NRV (Nutrient Reference Value) according to EU regulation
Safr’Inside™ is a trademark of Activ’inside. Quatrefolic® is a trademark and brand of GNOSIS S.p.A.
Store tightly closed and dry at below 25 °C.
Food supplements are not a substitute for a balanced, varied diet and a healthy lifestyle. The recommended daily dose should not be exceeded. Keep out of reach of children. The information provided is not intended as a substitute for advice from your physician or other health care professionals. It is not a statement on healing or a recommendation for self-medication.
When it comes to your health, quality is most important. Therefore our Vitality Nutritionals products undergo state of the art independent laboratory analysis to verify label claims and to ensure that you get the highest quality nutrition supplements.