Bones are not dead tissue but are constantly being built up and broken down. They consist of a hard shell and are filled with a fabric matrix.

Ideally, our entire skeleton is renewed every 7 years. This process is regulated by the osteoblasts (building cells) and osteoclasts (building cells). Osteoblasts produce vitamin K-dependent proteins called osteocalcin. This protein binds calcium in the bone matrix and ensures healthy bones.

From around the age of 35, there is increased activity of the osteoclasts, causing the bones to lose about 1 - 1.5% of substance per year. If this breakdown is faster than normal.

Vegans are particularly at risk of certain diseases. On the one hand, because they do not eat dairy products and absorb too little calcium. On the other hand, if they are exposed to too little sunlight, as is the case with most people in Europe, they also produce too little vitamin D in the skin. This leads to a vitamin D deficiency over a longer period and, together with the calcium deficiency.

Osteoxan contains the following vital nutrients which showed in studies to improve the build-up of strong bones.

Millions of people take calcium supplements and vitamin D to strengthen their bones. According to the latest scientific findings, these two vital substances alone are not sufficient for healthy bones.

Vitamin K2 showed in several studies to be as important for bone health as Calcium and Vitamin D3. Vitamin K2 activates Osteocalcin, a vitamin k-dependent protein that helps binding calcium in the bone matrix.

If someone lacks Vitamin K2 the bone density may decrease, even if this person gets enough Calcium and Vitamin D3. At the same time, the calcium which should be used for stable bones, is deposited in the artery walls, where it promotes calcification of the blood vessels.

As early as 1984, scientists observed that patients had 70% less vitamin K in serum than a comparison group of the same age. Studies show that people who consume higher amounts of vitamin K2 have stronger, healthier bones. Unfortunately, our environment does not contain enough natural vitamin K2, which means that a large part of the population has a vitamin K2 deficiency.

Calcium has for decades been the most obvious choice of dietary supplement for improving bone health. Even though it is the foundation for bone building, healthy bones also contain many other minerals and trace elements which are just as important as calcium, even though they are required in very small amounts.

It is also interesting that Osteoxan is not just calcium, but indeed a bioactive mineral mixture. In addition to calcium, it contains 73 other minerals and trace elements, such as magnesium, zinc, iron, manganese, copper, selenium, and many more. The amounts of these are very small, but in the complete mineral matrix, they have a synergistic effect and increase the effectiveness of the calcium it contains.

Although these occur in smaller quantities, they are significantly involved in building healthy bones. Studies show that calcium can only optimally promote the development of bones if it is taken together with other minerals and trace elements.

Vitamin D3 fulfils several tasks when building the bones. These include the absorption of calcium in the intestine and the formation of osteocalcin. This bone-specific protein helps to incorporate calcium into the bone matrix.

As mentioned previously, Osteocalcin also requires the presence of Vitamin K2 to fulfil its work. Therefore, Osteoxan contains 2,000 IU of vitamin D3 per daily dose. This dose is considered optimal and can also be taken daily in the long term.

Magnesium showed in several human studies that it may enhance bone density. Bones contain approximately 50% of the body's magnesium deposits. Magnesium deficiency can lead to certain diseases because it regulates those hormones which are responsible for proper calcium metabolism.

Boron is also very important for building healthy bones, because it supports the metabolism of calcium, magnesium and vitamin D. Boron reduces the excretion of calcium and magnesium in the urine.

This is especially important for women who are experiencing menopause because due to the reduced hormone levels they lose greater amounts of calcium and magnesium.

These trace elements are also very important for bone health and the preservation of bone density. Osteoxan supplies these trace elements in a very bioactive form, which can be absorbed very easily by the body.

These vitamins are essential for the build-up of Collagen Type I and other proteins, which account for 20% of the bone matrix. These collagen fibres are responsible for keeping the bones elastic and strong at the same time.

Early diagnosis of bone diseases is not easy because it develops gradually. The measurement of bone density often does not give sufficient clarity about this.

Usually, it is noticeable only through a stinging and pulling pain in the bones and the back, through a changed posture or through a spontaneous fracture of the bone, vertebral fracture, or fracture of the femur.

Only then are preparations usually prescribed that are intended to restore bone density. But these can hardly stop a process that has developed over decades, they can only delay it. If you want to do something about bone diseases, you should start at the age of 40 at the latest.

In general, calcium, vitamin D, adequate exercise, and 30 minutes of exposure to sunlight every day are recommended. The latest research shows that vitamin K2 and other important bone vital substances are also necessary to maintain healthy bones.

People who take anticoagulants or have a blood clotting disorder should consult their doctor before taking this product.

The reason for this is that the intake of more than 45 mcg of vitamin K2 per day has an effect on blood coagulation inhibitors based on coumarin, e.g. marcumar, could decrease. These work by inhibiting the effects of vitamin K2 in the body.

However, since our body absolutely needs vitamin K for healthy bones and clean arteries, we recommend not taking any vitamin K-dependent anticoagulants. Talk to your doctor about prescribing a preparation that works independently from vitamin K. These are known as direct oral anticoagulants (DOAK).